I don't see a source for her name being "Miriam" or her death in 1605 in Prague. Rosenstein, Vol. I, p. 17, just calls her Elder Daughter of Rabbi Shmuel Yehuda Katzenellenbogen, MaHaShiks, MaHaRaM son #1 Also there should be no children for this couple, Rabbi Eliyahu Ashkenazi and Rachel Katzenellenbogen