Extremely interesting journal article by Faustini says that POTENTIALLY an 'unknown named daughter' of Gershon Loans & Reisling married Rabbi Eleizer Zay (Rabbi Elieser Lipmann Zay, Friedberg)
Making Rabbi Elizer Zay and "Fille ( Pas De Nom ) De Reisel/Rose Et Gershon Loans" parents to Rabbi Gerson Zay of Metz (Rabbi Gerson Eliezer Zay)
Cercle de Généalogie Juive: Journal 125
"From Gerson Zay of Metz to Joselman of Rosheim" by Pascal Faustini
https://www.genealoj.org/en/revue-cercle/journal-125
I have not yet found any other evidence to support this theory, but it seems entirely possible. Thought I'd mention it for others out there to be aware. Zay family potential linked with the Loans/Spira family.